Characterization of ACE2 naturally occurring missense variants: impact on subcellular localization and trafficking

BACKGROUND: Human angiotensin-converting enzyme 2 (ACE2), a type I transmembrane receptor physiologically acting as a carboxypeptidase enzyme within the renin-angiotensin system (RAS), is a critical mediator of infection by several severe acute respiratory syndrome (SARS) corona viruses. For instanc...

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Detalles Bibliográficos
Autores principales: Badawi, Sally, Mohamed, Feda E., Alkhofash, Nesreen R., John, Anne, Ali, Amanat, Ali, Bassam R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438391/
https://www.ncbi.nlm.nih.gov/pubmed/36056420
http://dx.doi.org/10.1186/s40246-022-00411-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438391/
https://www.ncbi.nlm.nih.gov/pubmed/36056420
http://dx.doi.org/10.1186/s40246-022-00411-1

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