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Water-assisted and protein-initiated fast and controlled ring-opening polymerization of proline N-carboxyanhydride
The production of polypeptides via the ring-opening polymerization (ROP) of N-carboxyanhydride (NCA) is usually conducted under stringent anhydrous conditions. The ROP of proline NCA (ProNCA) for the synthesis of poly-(L)-proline (PLP) is particularly challenging due to the premature product precipi...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438472/ https://www.ncbi.nlm.nih.gov/pubmed/36072505 http://dx.doi.org/10.1093/nsr/nwac033 |