Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP

The 70 kDa heat-shock proteins (Hsp70s) are ATP-dependent molecular chaperones that contain an N-terminal nucleotide-binding domain (NBD) and a C-terminal substrate-binding domain. Hsp70s bind to misfolded/unfolded proteins and thereby prevent their aggregation. The ATP hydrolysis reaction in the NB...

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Detalles Bibliográficos
Autores principales: Yokoyama, Takeshi, Fujii, Shiho, Ostermann, Andreas, Schrader, Tobias E., Nabeshima, Yuko, Mizuguchi, Mineyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438496/
https://www.ncbi.nlm.nih.gov/pubmed/36071806
http://dx.doi.org/10.1107/S2052252522006297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438496/
https://www.ncbi.nlm.nih.gov/pubmed/36071806
http://dx.doi.org/10.1107/S2052252522006297

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