The tem­per­ature-dependent conformational ensemble of SARS-CoV-2 main protease (M(pro))

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The COVID-19 pandemic, instigated by the SARS-CoV-2 coronavirus, continues to plague the globe. The SARS-CoV-2 main protease, or M(pro), is a promising target for the development of novel antiviral therapeutics. Previous X-ray crystal structures of M(pro) were obtained at cryogenic tem­per­ature or...

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Detalles Bibliográficos
Autores principales: Ebrahim, Ali, Riley, Blake T., Kumaran, Desigan, Andi, Babak, Fuchs, Martin R., McSweeney, Sean, Keedy, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2022
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438506/
https://www.ncbi.nlm.nih.gov/pubmed/36071812
http://dx.doi.org/10.1107/S2052252522007497

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438506/
https://www.ncbi.nlm.nih.gov/pubmed/36071812
http://dx.doi.org/10.1107/S2052252522007497

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