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The temperature-dependent conformational ensemble of SARS-CoV-2 main protease (M(pro))
The COVID-19 pandemic, instigated by the SARS-CoV-2 coronavirus, continues to plague the globe. The SARS-CoV-2 main protease, or M(pro), is a promising target for the development of novel antiviral therapeutics. Previous X-ray crystal structures of M(pro) were obtained at cryogenic temperature or...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438506/ https://www.ncbi.nlm.nih.gov/pubmed/36071812 http://dx.doi.org/10.1107/S2052252522007497 |
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