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Lamina Propria Phagocyte Profiling Reveals Targetable Signaling Pathways in Refractory Inflammatory Bowel Disease

BACKGROUND AND AIMS: Lamina propria phagocytes are key mediators of inflammatory bowel disease (IBD). We aimed to understand the transcriptomic and functional differences in these cells based on location, disease type, inflammation state, and medication use in patients with IBD. METHODS: Phagocytic...

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Detalles Bibliográficos
Autores principales: Jacobsen, Gillian E., Fernández, Irina, Quintero, Maria A., Santander, Ana M., Pignac-Kobinger, Judith, Damas, Oriana M., Deshpande, Amar R., Kerman, David H., Ban, Yuguang, Gao, Zhen, Silva, Tiago C., Wang, Lily, Beecham, Ashley H., McCauley, Jacob L., Burgueño, Juan F., Abreu, Maria T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438737/
https://www.ncbi.nlm.nih.gov/pubmed/36061955
http://dx.doi.org/10.1016/j.gastha.2022.01.005