Multiethnic polygenic risk prediction in diverse populations through transfer learning

Polygenic risk scores (PRS) leverage the genetic contribution of an individual’s genotype to a complex trait by estimating disease risk. Traditional PRS prediction methods are predominantly for the European population. The accuracy of PRS prediction in non-European populations is diminished due to m...

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Detalles Bibliográficos
Autores principales: Tian, Peixin, Chan, Tsai Hor, Wang, Yong-Fei, Yang, Wanling, Yin, Guosheng, Zhang, Yan Dora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438789/
https://www.ncbi.nlm.nih.gov/pubmed/36061179
http://dx.doi.org/10.3389/fgene.2022.906965

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438789/
https://www.ncbi.nlm.nih.gov/pubmed/36061179
http://dx.doi.org/10.3389/fgene.2022.906965

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