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Meiotic DNA breaks activate a streamlined phospho-signaling response that largely avoids protein-level changes

Meiotic cells introduce a numerous programmed DNA breaks into their genome to stimulate meiotic recombination and ensure controlled chromosome inheritance and fertility. A checkpoint network involving key kinases and phosphatases coordinates the repair of these DNA breaks, but the precise phosphoryl...

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Detalles Bibliográficos
Autores principales: Kar, Funda M, Vogel, Christine, Hochwagen, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438802/
https://www.ncbi.nlm.nih.gov/pubmed/36271494
http://dx.doi.org/10.26508/lsa.202201454