The human RNA polymerase I structure reveals an HMG-like docking domain specific to metazoans

Transcription of the ribosomal RNA precursor by RNA polymerase (Pol) I is a major determinant of cellular growth, and dysregulation is observed in many cancer types. Here, we present the purification of human Pol I from cells carrying a genomic GFP fusion on the largest subunit allowing the structur...

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Detalles Bibliográficos
Autores principales: Daiß, Julia L, Pilsl, Michael, Straub, Kristina, Bleckmann, Andrea, Höcherl, Mona, Heiss, Florian B, Abascal-Palacios, Guillermo, Ramsay, Ewan P, Tlučková, Katarina, Mars, Jean-Clement, Fürtges, Torben, Bruckmann, Astrid, Rudack, Till, Bernecky, Carrie, Lamour, Valérie, Panov, Konstantin, Vannini, Alessandro, Moss, Tom, Engel, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438803/
https://www.ncbi.nlm.nih.gov/pubmed/36271492
http://dx.doi.org/10.26508/lsa.202201568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438803/
https://www.ncbi.nlm.nih.gov/pubmed/36271492
http://dx.doi.org/10.26508/lsa.202201568

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