Context matters – Daxx and Atrx are not robust tumor suppressors in the murine endocrine pancreas

Genome sequencing has revealed the importance of epigenetic regulators in tumorigenesis. The genes encoding the chromatin remodeling complex DAXX:ATRX are frequently mutated in pancreatic neuroendocrine tumors; however, the underlying mechanisms of how mutations contribute to tumorigenesis are only...

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Detalles Bibliográficos
Autores principales: Sun, Chang, Estrella, Jeannelyn S., Whitley, Elizabeth M., Chau, Gilda P., Lozano, Guillermina, Wasylishen, Amanda R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438929/
https://www.ncbi.nlm.nih.gov/pubmed/35976056
http://dx.doi.org/10.1242/dmm.049552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438929/
https://www.ncbi.nlm.nih.gov/pubmed/35976056
http://dx.doi.org/10.1242/dmm.049552

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