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Endoplasmic reticulum stress promoted acinar cell necroptosis in acute pancreatitis through cathepsinB-mediated AP-1 activation

Acinar cell death and inflammatory response are two important events which determine the severity of acute pancreatitis (AP). Endoplasmic reticulum (ER) stress and necroptosis are involved in this process, but the relationships between them remain unknown. Here, we analyzed the interaction between E...

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Detalles Bibliográficos
Autores principales: Han, Xiao, Li, Bin, Bao, Jingpiao, Wu, Zengkai, Chen, Congying, Ni, Jianbo, Shen, Jie, Song, Pengli, Peng, Qi, Wan, Rong, Wang, Xingpeng, Wu, Jianghong, Hu, Guoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438943/
https://www.ncbi.nlm.nih.gov/pubmed/36059491
http://dx.doi.org/10.3389/fimmu.2022.968639