Cargando…
Predicting and explaining the impact of genetic disruptions and interactions on organismal viability
MOTIVATION: Existing computational models can predict single- and double-mutant fitness but they do have limitations. First, they are often tested via evaluation metrics that are inappropriate for imbalanced datasets. Second, all of them only predict a binary outcome (viable or not, and negatively i...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9438956/ https://www.ncbi.nlm.nih.gov/pubmed/35861390 http://dx.doi.org/10.1093/bioinformatics/btac519 |