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STAG2 promotes the myelination transcriptional program in oligodendrocytes

Cohesin folds chromosomes via DNA loop extrusion. Cohesin-mediated chromosome loops regulate transcription by shaping long-range enhancer–promoter interactions, among other mechanisms. Mutations of cohesin subunits and regulators cause human developmental diseases termed cohesinopathy. Vertebrate co...

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Detalles Bibliográficos
Autores principales: Cheng, Ningyan, Li, Guanchen, Kanchwala, Mohammed, Evers, Bret M, Xing, Chao, Yu, Hongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439679/
https://www.ncbi.nlm.nih.gov/pubmed/35959892
http://dx.doi.org/10.7554/eLife.77848