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Antioxidative and Anti-Inflammatory Protective Effects of β-Caryophyllene against Amikacin-Induced Nephrotoxicity in Rat by Regulating the Nrf2/AMPK/AKT and NF-κB/TGF-β/KIM-1 Molecular Pathways

Herein, the molecular pathogenic pathways implicated in renal injury triggered by amikacin (AK), together with the alleviating actions of β-caryophyllene (BCP), were investigated. Adult male Wistar rats (n = 32) were disseminated to the four following groups (n = 8/group): normal group, positive con...

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Detalles Bibliográficos
Autores principales: Rajab, Bodour S., Albukhari, Talat A., Khan, Anmar A., Refaat, Bassem, Almehmadi, Samah J., Nasreldin, Nani, Elshopakey, Gehad E., El-Boshy, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439917/
https://www.ncbi.nlm.nih.gov/pubmed/36062191
http://dx.doi.org/10.1155/2022/4212331