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Histone acetylome-wide associations in immune cells from individuals with active Mycobacterium tuberculosis infection

Host cell chromatin changes are thought to play an important role in the pathogenesis of infectious diseases. Here we describe a histone acetylome-wide association study (HAWAS) of an infectious disease, on the basis of genome-wide H3K27 acetylation profiling of peripheral blood granulocytes and mon...

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Detalles Bibliográficos
Autores principales: del Rosario, Ricardo C. H., Poschmann, Jeremie, Lim, Carey, Cheng, Catherine Y., Kumar, Pavanish, Riou, Catherine, Ong, Seow Theng, Gerges, Sherif, Hajan, Hajira Shreen, Kumar, Dilip, Marzuki, Mardiana, Lu, Xiaohua, Lee, Andrea, Wijaya, Giovani Claresta, Rayan, Nirmala Arul, Zhuang, Zhong, Du Bruyn, Elsa, Chee, Cynthia Bin Eng, Lee, Bernett, Lum, Josephine, Zolezzi, Francesca, Poidinger, Michael, Rotzschke, Olaf, Khor, Chiea Chuen, Wilkinson, Robert J., Wang, Yee T., Chandy, George K, De Libero, Gennaro, Singhal, Amit, Prabhakar, Shyam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439955/
https://www.ncbi.nlm.nih.gov/pubmed/35102304
http://dx.doi.org/10.1038/s41564-021-01049-w