miR-539-5p regulates Srebf1 transcription in the skeletal muscle of diabetic mice by targeting DNA methyltransferase 3b

Aberrant DNA methylation is associated with diabetes, but the precise regulatory events that control the levels and activity of DNA methyltransferases (DNMTs) is not well understood. Here we show that miR-539-5p targets Dnmt3b and regulates its cellular levels. miR-539-5p and Dnmt3b show inverse pat...

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Detalles Bibliográficos
Autores principales: Kesharwani, Devesh, Kumar, Amit, Rizvi, Ashima, Datta, Malabika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439965/
https://www.ncbi.nlm.nih.gov/pubmed/36090753
http://dx.doi.org/10.1016/j.omtn.2022.08.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439965/
https://www.ncbi.nlm.nih.gov/pubmed/36090753
http://dx.doi.org/10.1016/j.omtn.2022.08.013

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