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An approach to assess and adjust for the influence of multicollinear covariates on metabolomics association patterns—applied to a study of the associations between a comprehensive lipoprotein profile and the homeostatic model assessment of insulin resistance

INTRODUCTION: Comprehensive lipoprotein profiling using proton nuclear magnetic resonance (NMR) spectroscopy of serum represents an alternative to the homeostatic model assessment of insulin resistance (HOMA-IR). Both adiposity and physical (in)activity associate to insulin resistance, but quantific...

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Detalles Bibliográficos
Autores principales: Kvalheim, Olav M., Rajalahti, Tarja, Aadland, Eivind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9439979/
https://www.ncbi.nlm.nih.gov/pubmed/36056220
http://dx.doi.org/10.1007/s11306-022-01931-6