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Mitochondrial Ca(2+) uptake by the MCU facilitates pyramidal neuron excitability and metabolism during action potential firing
Neuronal activation is fundamental to information processing by the brain and requires mitochondrial energy metabolism. Mitochondrial Ca(2+) uptake by the mitochondrial Ca(2+) uniporter (MCU) has long been implicated in the control of energy metabolism and intracellular Ca(2+) signalling, but its im...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440007/ https://www.ncbi.nlm.nih.gov/pubmed/36056095 http://dx.doi.org/10.1038/s42003-022-03848-1 |