Downregulation of Elovl5 promotes breast cancer metastasis through a lipid-droplet accumulation-mediated induction of TGF-β receptors

Metastatic breast cancer cannot be cured, and alteration of fatty acid metabolism contributes to tumor progression and metastasis. Here, we were interested in the elongation of very long-chain fatty acids protein 5 (Elovl5) in breast cancer. We observed that breast cancer tumors had a lower expressi...

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Detalles Bibliográficos
Autores principales: Kieu, Trinh-Le-Vi, Pierre, Léa, Derangère, Valentin, Perrey, Sabrina, Truntzer, Caroline, Jalil, Antoine, Causse, Sébastien, Groetz, Emma, Dumont, Adélie, Guyard, Laura, Arnould, Laurent, de Barros, Jean-Paul Pais, Apetoh, Lionel, Rébé, Cédric, Limagne, Emeric, Jourdan, Tony, Demizieux, Laurent, Masson, David, Thomas, Charles, Ghiringhelli, François, Rialland, Mickaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440092/
https://www.ncbi.nlm.nih.gov/pubmed/36056008
http://dx.doi.org/10.1038/s41419-022-05209-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440092/
https://www.ncbi.nlm.nih.gov/pubmed/36056008
http://dx.doi.org/10.1038/s41419-022-05209-6

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