Suppression of exaggerated NMDAR activity by memantine treatment ameliorates neurological and behavioral deficits in aminopeptidase P1-deficient mice

Inborn errors of metabolism (IEMs) are common causes of neurodevelopmental disorders, including microcephaly, hyperactivity, and intellectual disability. However, the synaptic mechanisms of and pharmacological interventions for the neurological complications of most IEMs are unclear. Here, we report...

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Detalles Bibliográficos
Autores principales: Bae, Young-Soo, Yoon, Sang Ho, Kim, Young Sook, Oh, Sung Pyo, Song, Woo Seok, Cha, Jin Hee, Kim, Myoung-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440093/
https://www.ncbi.nlm.nih.gov/pubmed/35922532
http://dx.doi.org/10.1038/s12276-022-00818-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440093/
https://www.ncbi.nlm.nih.gov/pubmed/35922532
http://dx.doi.org/10.1038/s12276-022-00818-9

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