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Adult fibroblasts use aggresomes only in distinct cell-states

The aggresome is a protein turnover system in which proteins are trafficked along microtubules to the centrosome for degradation. Despite extensive focus on aggresomes in immortalized cell lines, it remains unclear if the aggresome is conserved in all primary cells and all cell-states. Here we exami...

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Detalles Bibliográficos
Autores principales: Morrow, Christopher S., Arndt, Zachary P., Klosa, Payton C., Peng, Bo, Zewdie, Eden Y., Benayoun, Bérénice A., Moore, Darcie L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440096/
https://www.ncbi.nlm.nih.gov/pubmed/36056070
http://dx.doi.org/10.1038/s41598-022-19055-1