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AMPK suppresses Th2 cell responses by repressing mTORC2

Allergic inflammation is a T helper 2 (Th2) cell-driven pathophysiological phenomenon, but the mechanism by which the metabolic cascade affects Th2 cell differentiation remains unclear. In this study, we investigated the roles of AMP-activated protein kinase (AMPK) and intracellular energy sensors i...

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Detalles Bibliográficos
Autores principales: Pandit, Mahesh, Timilshina, Maheshwor, Gu, Ye, Acharya, Suman, Chung, Yeonseok, Seo, Sang-Uk, Chang, Jae-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440126/
https://www.ncbi.nlm.nih.gov/pubmed/35999454
http://dx.doi.org/10.1038/s12276-022-00832-x