Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling

Astrocytes are important components of the innate immune response in the central nervous system (CNS), involving in the inflammatory and neurotoxic responses that occur in CNS diseases, such as multiple sclerosis (MS). Recent studies have shown that SARM1 plays a critical role in axonal degeneration...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Lingting, Zhang, Jingjing, Hua, Xin, Xu, Xingxing, Li, Jia, Wang, Jiaojiao, Wang, Mianxian, Liu, Huitao, Qiu, Haoyu, Chen, Man, Zhang, Xu, Wang, Ying, Huang, Zhihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440144/
https://www.ncbi.nlm.nih.gov/pubmed/36055989
http://dx.doi.org/10.1038/s41419-022-05202-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440144/
https://www.ncbi.nlm.nih.gov/pubmed/36055989
http://dx.doi.org/10.1038/s41419-022-05202-z

Ejemplares similares