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Mechanosensitive expression of the mesenchymal subtype marker connective tissue growth factor in glioblastoma

Mechanical forces created by the extracellular environment regulate biochemical signals that modulate the inter-related cellular phenotypes of morphology, proliferation, and migration. A stiff microenvironment induces glioblastoma (GBM) cells to develop prominent actin stress fibres, take on a sprea...

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Detalles Bibliográficos
Autores principales: Grundy, Thomas James, Orcheston-Findlay, Louise, de Silva, Eshana, Jegathees, Thuvarahan, Prior, Victoria, Sarker, Farhana Amy, O’Neill, Geraldine Margaret
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440209/
https://www.ncbi.nlm.nih.gov/pubmed/36056123
http://dx.doi.org/10.1038/s41598-022-19175-8