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Mechanosensitive expression of the mesenchymal subtype marker connective tissue growth factor in glioblastoma
Mechanical forces created by the extracellular environment regulate biochemical signals that modulate the inter-related cellular phenotypes of morphology, proliferation, and migration. A stiff microenvironment induces glioblastoma (GBM) cells to develop prominent actin stress fibres, take on a sprea...
Autores principales: | Grundy, Thomas James, Orcheston-Findlay, Louise, de Silva, Eshana, Jegathees, Thuvarahan, Prior, Victoria, Sarker, Farhana Amy, O’Neill, Geraldine Margaret |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440209/ https://www.ncbi.nlm.nih.gov/pubmed/36056123 http://dx.doi.org/10.1038/s41598-022-19175-8 |
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