Phosphodiesterase 4D contributes to angiotensin II-induced abdominal aortic aneurysm through smooth muscle cell apoptosis

Abdominal aortic aneurysm (AAA) is a permanent expansion of the abdominal aorta that has a high mortality but limited treatment options. Phosphodiesterase (PDE) 4 family members are cAMP-specific hydrolyzing enzymes and have four isoforms (PDE4A-PDE4D). Several pan-PDE4 inhibitors are used clinicall...

Descripción completa

Detalles Bibliográficos
Autores principales: Gao, Ran, Guo, Wenjun, Fan, Tianfei, Pang, Junling, Hou, Yangfeng, Feng, Xiaohang, Li, Bolun, Ge, Weipeng, Fan, Tianhui, Zhang, Tiantian, Lu, Jiakai, Jing, He, Jin, Mu, Yan, Chen, Wang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440214/
https://www.ncbi.nlm.nih.gov/pubmed/35999453
http://dx.doi.org/10.1038/s12276-022-00815-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440214/
https://www.ncbi.nlm.nih.gov/pubmed/35999453
http://dx.doi.org/10.1038/s12276-022-00815-y

Ejemplares similares