ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control

Multiple preclinical studies have shown improved outcomes when radiation therapy is combined with immune modulating antibodies. However, to date, many of these promising results have failed to translate to successful clinical studies. This led us to explore additional checkpoint and co-stimulatory p...

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Detalles Bibliográficos
Autores principales: Blair, Tiffany, Baird, Jason, Bambina, Shelly, Kramer, Gwen, Gostissa, Monica, Harvey, Christopher J., Gough, Michael J., Crittenden, Marka R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440216/
https://www.ncbi.nlm.nih.gov/pubmed/36056093
http://dx.doi.org/10.1038/s41598-022-19256-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440216/
https://www.ncbi.nlm.nih.gov/pubmed/36056093
http://dx.doi.org/10.1038/s41598-022-19256-8

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