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ICOS is upregulated on T cells following radiation and agonism combined with radiation results in enhanced tumor control
Multiple preclinical studies have shown improved outcomes when radiation therapy is combined with immune modulating antibodies. However, to date, many of these promising results have failed to translate to successful clinical studies. This led us to explore additional checkpoint and co-stimulatory p...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440216/ https://www.ncbi.nlm.nih.gov/pubmed/36056093 http://dx.doi.org/10.1038/s41598-022-19256-8 |