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Chimeric natural products derived from medermycin and the nature-inspired construction of their polycyclic skeletons

Medermycin, produced by Streptomyces species, represents a family of antibiotics with significant activity against Gram-positive pathogens. The biosynthesis of this family of natural products has been studied, and new skeletons related to medermycin have rarely been reported until recently. Herein,...

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Detalles Bibliográficos
Autores principales: Yin, Shupeng, Liu, Zhi, Shen, Jingjing, Xia, Yuwei, Wang, Weihong, Gui, Pengyan, Jia, Qian, Kachanuban, Konthorn, Zhu, Weiming, Fu, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440243/
https://www.ncbi.nlm.nih.gov/pubmed/36056035
http://dx.doi.org/10.1038/s41467-022-32901-0