Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages

Peritoneal dissemination of ovarian cancer (OC) correlates with poor prognosis, but the mechanisms underlying the escape of OC cells from the intraperitoneal immune system have remained unknown. We here identify pigment epithelium–derived factor (PEDF) as a promoting factor of OC dissemination, whic...

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Detalles Bibliográficos
Autores principales: Ueno, Sayaka, Sudo, Tamotsu, Saya, Hideyuki, Sugihara, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440245/
https://www.ncbi.nlm.nih.gov/pubmed/36056141
http://dx.doi.org/10.1038/s42003-022-03837-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440245/
https://www.ncbi.nlm.nih.gov/pubmed/36056141
http://dx.doi.org/10.1038/s42003-022-03837-4

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