Cargando…

Pigment epithelium-derived factor promotes peritoneal dissemination of ovarian cancer through induction of immunosuppressive macrophages

Peritoneal dissemination of ovarian cancer (OC) correlates with poor prognosis, but the mechanisms underlying the escape of OC cells from the intraperitoneal immune system have remained unknown. We here identify pigment epithelium–derived factor (PEDF) as a promoting factor of OC dissemination, whic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ueno, Sayaka, Sudo, Tamotsu, Saya, Hideyuki, Sugihara, Eiji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440245/ https://www.ncbi.nlm.nih.gov/pubmed/36056141 http://dx.doi.org/10.1038/s42003-022-03837-4

Ejemplares similares

Obesity-Induced Peritoneal Dissemination of Ovarian Cancer and Dominant Recruitment of Macrophages in Ascites
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2018)

Laparoscopic Gastrectomy for Gastric Cancer with Peritoneal Dissemination after Induction Chemotherapy
por: Tsutsumi, Satoshi, et al.
Publicado: (2013)

OX40 ligand expression abrogates the immunosuppressive function of retinal pigment epithelium
por: Cunningham, Matthew A, et al.
Publicado: (2013)

ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors
por: Ueno, Sayaka, et al.
Publicado: (2022)

Efficient induction of productive Cre-mediated recombination in retinal pigment epithelium
por: Fu, Shuhua, et al.
Publicado: (2014)

The Effect of Abdominal Radical Trachelectomy on Ovarian Reserve: Serial Changes in Serum Anti-Müllerian Hormone Levels
por: Muraji, Miho, et al.
Publicado: (2012)

Cancer-associated fibroblasts promote an immunosuppressive microenvironment through the induction and accumulation of protumoral macrophages
por: Takahashi, Hideyuki, et al.
Publicado: (2016)

Detection of Retinal Pigment Epithelium-Specific Antibody in iPSC-Derived Retinal Pigment Epithelium Transplantation Models
por: Sugita, Sunao, et al.
Publicado: (2017)

Retinal Pigment Epithelium Derived Stem Cells
por: Hiscott, Paul, et al.
Publicado: (2009)

Bestrophin 2 is expressed in human non-pigmented ciliary epithelium but not retinal pigment epithelium
por: Zhang, Youwen, et al.
Publicado: (2010)

Regulation of invasion and peritoneal dissemination of ovarian cancer by mesothelin manipulation
por: Coelho, Ricardo, et al.
Publicado: (2020)

PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression
por: Prat, Mélissa, et al.
Publicado: (2023)

Pigment Epithelium-Derived Factor Secreted from Retinal Pigment Epithelium Facilitates Apoptotic Cell Death of iPSC
por: Kanemura, Hoshimi, et al.
Publicado: (2013)

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)
por: Bullock, Jeanee, et al.
Publicado: (2021)

Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.
por: Bennis, A., et al.
Publicado: (2017)

Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment
por: Miura, Masahiro, et al.
Publicado: (2019)

Periostin antisense oligonucleotide suppresses bleomycin‐induced formation of a lung premetastatic niche for melanoma
por: Semba, Takashi, et al.
Publicado: (2018)

Increased levels of serum pigment epithelium-derived factor aggravate proteinuria via induction of podocyte actin rearrangement
por: Huang, Na, et al.
Publicado: (2018)

Pigment epithelium-derived factor in lipid metabolic disorders
por: Huang, Kuang-Tzu, et al.
Publicado: (2018)

Translocation of the retinal pigment epithelium and formation of sub-retinal pigment epithelium deposit induced by subretinal deposit
por: Zhao, Lian, et al.
Publicado: (2007)

Expression of CD24 is associated with HER2 expression and supports HER2-Akt signaling in HER2-positive breast cancer cells
por: Hosonaga, Mari, et al.
Publicado: (2014)

Depletion of R270C Mutant p53 in Osteosarcoma Attenuates Cell Growth but Does Not Prevent Invasion and Metastasis In Vivo
por: Shimizu, Takatsune, et al.
Publicado: (2022)

Adenoma of the Ciliary Pigment Epithelium with Diffuse Iris Pigment Dispersion
por: Chang, Ying, et al.
Publicado: (2015)

Induction of cystine transport activity in mouse peritoneal macrophages
Publicado: (1987)

Disseminated Microsporidiosis in an Immunosuppressed Patient
por: Meissner, Eric G., et al.
Publicado: (2012)

Setting Eyes on the Retinal Pigment Epithelium
por: Moreno-Marmol, Tania, et al.
Publicado: (2018)

Functions and Diseases of the Retinal Pigment Epithelium
por: Yang, Song, et al.
Publicado: (2021)

Impact of drusen and drusenoid retinal pigment epithelium elevation size and structure on the integrity of the retinal pigment epithelium layer
por: Schlanitz, Ferdinand, et al.
Publicado: (2019)

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium
por: Zhu, Zhe, et al.
Publicado: (2022)

Disseminated Mycobacterium avium Complex Infection in a Patient Treated With Immunosuppressants
por: Ito, Yuki, et al.
Publicado: (2023)

Disseminated Peritoneal Leiomyomatosis
por: Momtahan, Mozhdeh, et al.
Publicado: (2011)

Impairing autophagy in retinal pigment epithelium leads to inflammasome activation and enhanced macrophage-mediated angiogenesis
por: Liu, Jian, et al.
Publicado: (2016)

TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer
por: Lecker, Laura S.M., et al.
Publicado: (2021)

Pigment epithelium-derived factor protects retinal ganglion cells
por: Pang, Iok-Hou, et al.
Publicado: (2007)

Pigment Epithelium-Derived Factor: Chemistry, Structure, Biology, and Applications
por: Becerra, S. Patricia, et al.
Publicado: (2012)

Pigment Epithelium-Derived Factor and Sex Hormone-Responsive Cancers
por: Brook, Naomi, et al.
Publicado: (2020)

Significance of vascular endothelial growth factor in growth and peritoneal dissemination of ovarian cancer
por: Masoumi Moghaddam, Samar, et al.
Publicado: (2011)

Gastrointestinal stromal tumor coexisting with disseminated peritoneal leiomyomatosis
por: Akamine, Kenri, et al.
Publicado: (2019)

Aggressive surgery could overcome the extent of initial peritoneal dissemination for advanced ovarian, fallopian tube, and peritoneal carcinoma
por: Nishikimi, Kyoko, et al.
Publicado: (2020)

Transcriptional comparison of adult human primary Retinal Pigment Epithelium, human pluripotent stem cell-derived Retinal Pigment Epithelium, and ARPE19 cells
por: Markert, Elke K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_jpp94877502ks7nsbvgcio0l0q