Pharmacological inhibition and reversal of pancreatic acinar ductal metaplasia

Pancreatic acinar cells display a remarkable degree of plasticity and can dedifferentiate into ductal-like progenitor cells by a process known as acinar ductal metaplasia (ADM). ADM is believed to be one of the earliest precursor lesions toward the development of pancreatic ductal adenocarcinoma and...

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Detalles Bibliográficos
Autores principales: da Silva, Lais, Jiang, Jinmai, Perkins, Corey, Atanasova, Kalina Rosenova, Bray, Julie K., Bulut, Gamze, Azevedo-Pouly, Ana, Campbell-Thompson, Martha, Yang, Xiaozhi, Hakimjavadi, Hesamedin, Chamala, Srikar, Ratnayake, Ranjala, Gharaibeh, Raad Z., Li, Chenglong, Luesch, Hendrik, Schmittgen, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440259/
https://www.ncbi.nlm.nih.gov/pubmed/36055991
http://dx.doi.org/10.1038/s41420-022-01165-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440259/
https://www.ncbi.nlm.nih.gov/pubmed/36055991
http://dx.doi.org/10.1038/s41420-022-01165-4

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