Cargando…

Phosphorylation of BRCA1 by ATM upon double-strand breaks impacts ATM function in end-resection: A potential feedback loop

BRCA1 maintains genome stability by promoting homologous recombination (HR)-mediated DNA double-strand break (DSB) repair. Mutation of mouse BRCA1-S1152, corresponding to an ATM phosphorylation site in its human counterpart, resulted in increased genomic instability and tumor incidence. In this stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Leilei, Chakravarthy, Reka, Li, Monica M., Deng, Chu-Xia, Li, Rong, Hu, Yanfen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440284/ https://www.ncbi.nlm.nih.gov/pubmed/36065181 http://dx.doi.org/10.1016/j.isci.2022.104944

Ejemplares similares

ATM specifically mediates repair of double-strand breaks with blocked DNA ends
por: Álvarez-Quilón, Alejandro, et al.
Publicado: (2014)

ATM controls meiotic double-strand break formation
por: Lange, Julian, et al.
Publicado: (2011)

ATM’s Role in the Repair of DNA Double-Strand Breaks
por: Shibata, Atsushi, et al.
Publicado: (2021)

NBN Phosphorylation regulates the accumulation of MRN and ATM at sites of DNA Double-Strand Breaks
por: Wen, Jie, et al.
Publicado: (2012)

The PARP3- and ATM-dependent phosphorylation of APLF facilitates DNA double-strand break repair
por: Fenton, Amanda L., et al.
Publicado: (2013)

Breaking up with ATM
por: Adamowicz, Marek
Publicado: (2018)

ATM Release at Resected Double-Strand Breaks Provides Heterochromatin Reconstitution to Facilitate Homologous Recombination
por: Geuting, Verena, et al.
Publicado: (2013)

ATM antagonizes NHEJ proteins assembly and DNA-ends synapsis at single-ended DNA double strand breaks
por: Britton, Sébastien, et al.
Publicado: (2020)

ATM regulates ATR chromatin loading in response to DNA double-strand breaks
por: Cuadrado, Myriam, et al.
Publicado: (2006)

Non-redundant Functions of ATM and DNA-PKcs in Response to DNA Double-Strand Breaks
por: Caron, Pierre, et al.
Publicado: (2015)

Coping with DNA Double-Strand Breaks via ATM Signaling Pathway in Bovine Oocytes
por: Wang, Lili, et al.
Publicado: (2020)

XAB2 promotes Ku eviction from single-ended DNA double-strand breaks independently of the ATM kinase
por: Sharma, Abhishek Bharadwaj, et al.
Publicado: (2021)

Abnormality of the DNA double-strand-break checkpoint/repair genes, ATM, BRCA1 and TP53, in breast cancer is related to tumour grade
por: Ding, S L, et al.
Publicado: (2004)

A Mathematical Model for the Detection Mechanism of DNA Double-Strand Breaks Depending on Autophosphorylation of ATM
por: Mouri, Kazunari, et al.
Publicado: (2009)

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase
por: Köcher, Sabrina, et al.
Publicado: (2012)

Downregulation of ATM and BRCA1 Predicts Poor Outcome in Head and Neck Cancer: Implications for ATM-Targeted Therapy
por: Wang, Yu-Chu, et al.
Publicado: (2021)

Yeast ATM and ATR kinases use different mechanisms to spread histone H2A phosphorylation around a DNA double-strand break
por: Li, Kevin, et al.
Publicado: (2020)

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
por: Beucher, Andrea, et al.
Publicado: (2009)

ATM Limits Incorrect End Utilization during Non-Homologous End Joining of Multiple Chromosome Breaks
por: Bennardo, Nicole, et al.
Publicado: (2010)

Wip1 and ATM in tumor evolution: role for BRCA1
por: Filipponi, Doria, et al.
Publicado: (2013)

Phosphorylation of SMURF2 by ATM exerts a negative feedback control of DNA damage response
por: Tang, Liu-Ya, et al.
Publicado: (2021)

Dynamic Dependence on ATR and ATM for Double-Strand Break Repair in Human Embryonic Stem Cells and Neural Descendants
por: Adams, Bret R., et al.
Publicado: (2010)

Requirement of ATM-dependent pathway for the repair of a subset of DNA double strand breaks created by restriction endonucleases
por: Suzuki, Keiji, et al.
Publicado: (2010)

ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells
por: Becker, Annabelle, et al.
Publicado: (2014)

Nuclear poly(A)-binding protein 1 is an ATM target and essential for DNA double-strand break repair
por: Gavish-Izakson, Michal, et al.
Publicado: (2018)

Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks
por: Ha, Geun-Hyoung, et al.
Publicado: (2019)

ATM controls meiotic DNA double-strand break formation and recombination and affects synaptonemal complex organization in plants
por: Kurzbauer, Marie-Therese, et al.
Publicado: (2021)

DNA Double-Strand Breaks Induced in Human Cells by 6 Current Pesticides: Intercomparisons and Influence of the ATM Protein
por: Sonzogni, Laurène, et al.
Publicado: (2022)

Selective Inhibition of ATM-dependent Double-strand Break Repair and Checkpoint Control Synergistically Enhances the Efficacy of ATR Inhibitors
por: Turchick, Audrey, et al.
Publicado: (2023)

A New Class of Selective ATM Inhibitors as Combination Partners of DNA Double-Strand Break Inducing Cancer Therapies
por: Zimmermann, Astrid, et al.
Publicado: (2022)

Reseaux ATM
por: Boisseau, Marc, et al.
Publicado: (1994)

ATM in senescence
por: Aird, Katherine M., et al.
Publicado: (2015)

Mechanisms of increased risk of tumorigenesis in Atm and Brca1 double heterozygosity
por: Wang, Jufang, et al.
Publicado: (2011)

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
por: Bakr, A., et al.
Publicado: (2015)

ATM: Functions of ATM Kinase and Its Relevance to Hereditary Tumors
por: Ueno, Sayaka, et al.
Publicado: (2022)

Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways
por: Wang, Minli, et al.
Publicado: (2013)

The Interaction of CtIP and Nbs1 Connects CDK and ATM to Regulate HR–Mediated Double-Strand Break Repair
por: Wang, Hailong, et al.
Publicado: (2013)

Abnormal Expression of DNA Double-Strand Breaks Related Genes, ATM and GammaH2AX, in Thyroid Carcinoma
por: Hu, Jin-lin, et al.
Publicado: (2015)

TRIP13 Participates in Immediate-Early Sensing of DNA Strand Breaks and ATM Signaling Amplification through MRE11
por: Jeong, Hyeongsun, et al.
Publicado: (2022)

ATM-SPARK: A GFP phase separation–based activity reporter of ATM
por: Li, Xiaoquan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_jt5dglhgsi15pt6bum3m2rt67q