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GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A

GINS1 is a GINS complex subunit that functions along with the MCM2-7 complex and Cdc45 in eukaryotic DNA replication. Despite the significance of the GINS complex in the switch between quiescence and proliferation of glioma cells inside and outside the perinecrotic niche, the biological functions an...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Liu, Xiaocen, Zhu, Xiaolong, Zhang, Mengying, Wang, Yingying, Ma, Mingzhe, Lv, Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
https://www.ncbi.nlm.nih.gov/pubmed/36065190
http://dx.doi.org/10.1016/j.isci.2022.104952