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GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
GINS1 is a GINS complex subunit that functions along with the MCM2-7 complex and Cdc45 in eukaryotic DNA replication. Despite the significance of the GINS complex in the switch between quiescence and proliferation of glioma cells inside and outside the perinecrotic niche, the biological functions an...
Autores principales: | Yang, Hui, Liu, Xiaocen, Zhu, Xiaolong, Zhang, Mengying, Wang, Yingying, Ma, Mingzhe, Lv, Kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440292/ https://www.ncbi.nlm.nih.gov/pubmed/36065190 http://dx.doi.org/10.1016/j.isci.2022.104952 |
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