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Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress
Mutations in ERCC2/XPD helicase, an important component of the TFIIH complex, cause distinct human genetic disorders which exhibit various pathological features. However, the molecular mechanisms underlying many symptoms remain elusive. Here, we have shown that Ercc2/Xpd deficiency in zebrafish resu...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440294/ https://www.ncbi.nlm.nih.gov/pubmed/36065184 http://dx.doi.org/10.1016/j.isci.2022.104957 |