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Ercc2/Xpd deficiency results in failure of digestive organ growth in zebrafish with elevated nucleolar stress

Mutations in ERCC2/XPD helicase, an important component of the TFIIH complex, cause distinct human genetic disorders which exhibit various pathological features. However, the molecular mechanisms underlying many symptoms remain elusive. Here, we have shown that Ercc2/Xpd deficiency in zebrafish resu...

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Detalles Bibliográficos
Autores principales: Ma, Jinmin, Shao, Xuelian, Geng, Fang, Liang, Shuzhang, Yu, Chunxiao, Zhang, Ruilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440294/
https://www.ncbi.nlm.nih.gov/pubmed/36065184
http://dx.doi.org/10.1016/j.isci.2022.104957