Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress

The inter-relationship between microglia dynamics and oxidative stress (Ox-stress) in dystrophic neurites (DNs) at Alzheimer’s Disease (AD) plaques may contribute to the pathological changes in neurons. We developed new in vivo imaging strategies to combine EGFP expression in microglia with neuronal...

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Detalles Bibliográficos
Autores principales: Wendt, Stefan, Johnson, Sora, Weilinger, Nicholas L., Groten, Christopher, Sorrentino, Stefano, Frew, Jonathan, Yang, Lucy, Choi, Hyun B., Nygaard, Haakon B., MacVicar, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440309/
https://www.ncbi.nlm.nih.gov/pubmed/36037587
http://dx.doi.org/10.1016/j.redox.2022.102448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440309/
https://www.ncbi.nlm.nih.gov/pubmed/36037587
http://dx.doi.org/10.1016/j.redox.2022.102448

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