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Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels

Parenteral administrations are a mainstay of clinical drug delivery. Intramuscular (IM) injections deposit drug directly into skeletal muscle bellies, providing rapid systemic uptake due to the highly vascularized nature of this site. The potential to inject particulate or non-aqueous materials have...

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Detalles Bibliográficos
Autores principales: McCartan, Adam, Mackay, Julia, Curran, David, Mrsny, Randall J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440386/
https://www.ncbi.nlm.nih.gov/pubmed/36065415
http://dx.doi.org/10.1016/j.ijpx.2022.100125