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Modelling intramuscular drug fate in vitro with tissue-relevant biomimetic hydrogels
Parenteral administrations are a mainstay of clinical drug delivery. Intramuscular (IM) injections deposit drug directly into skeletal muscle bellies, providing rapid systemic uptake due to the highly vascularized nature of this site. The potential to inject particulate or non-aqueous materials have...
Autores principales: | McCartan, Adam, Mackay, Julia, Curran, David, Mrsny, Randall J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440386/ https://www.ncbi.nlm.nih.gov/pubmed/36065415 http://dx.doi.org/10.1016/j.ijpx.2022.100125 |
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