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Maternal high-cholesterol diet negatively programs offspring bone development and downregulates hedgehog signaling in osteoblasts

Cholesterol is one of the essential intrauterine factors required for fetal growth and development. Maternal high cholesterol levels are known to be detrimental for offspring health. However, its long-term effect on offspring skeletal development remains to be elucidated. We performed our studies in...

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Detalles Bibliográficos
Autores principales: Mangu, SVVS Ravi, Patel, Kalpana, Sukhdeo, Shinde Vijay, Savitha, M.R., Sharan, Kunal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440389/
https://www.ncbi.nlm.nih.gov/pubmed/35931113
http://dx.doi.org/10.1016/j.jbc.2022.102324