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The controversial role and therapeutic development of the m6A demethylase FTO in renal cell carcinoma
Fat mass and obesity-associated (FTO) protein, the first m(6)A demethylase identified in 2011, regulates multiple aspects of RNA biology including splicing, localization, stability, and translation. Accumulating data show that FTO is involved in numerous physiological processes and is implicated in...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440419/ https://www.ncbi.nlm.nih.gov/pubmed/36037557 http://dx.doi.org/10.1016/j.tranon.2022.101518 |