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Mixed-dimensional multi-scale poroelastic modeling of adipose tissue for subcutaneous injection

Subcutaneous injection of therapeutic monoclonal antibodies (mAbs) has gained increasing interest in the pharmaceutical industry. The transport, distribution and absorption of mAbs in the skin after injection are not yet well-understood. Experiments have shown that fibrous septa form preferential ch...

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Detalles Bibliográficos
Autores principales: Leng, Yu, Wang, Hao, de Lucio, Mario, Gomez, Hector
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440471/
https://www.ncbi.nlm.nih.gov/pubmed/36057050
http://dx.doi.org/10.1007/s10237-022-01622-0