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Large extracellular vesicles secreted by human iPSC-derived MSCs ameliorate tendinopathy via regulating macrophage heterogeneity

Tendinopathy is a common musculoskeletal disorder which results in chronic pain and reduced performance. The therapeutic effect of stem cell derived-small extracellular vesicles (sEVs) for tendinopathy has been validated in recent years. However, whether large extracellular vesicles (lEVs), another...

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Detalles Bibliográficos
Autores principales: Ye, Teng, Chen, Zhengsheng, Zhang, Jieyuan, Luo, Lei, Gao, Renzhi, Gong, Liangzhi, Du, Yuhang, Xie, Zongping, Zhao, Bizeng, Li, Qing, Wang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440485/
https://www.ncbi.nlm.nih.gov/pubmed/36101856
http://dx.doi.org/10.1016/j.bioactmat.2022.08.007