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The absence of AhR in CD4(+) T cells in patients with acute graft-versus-host disease may be related to insufficient CTCF expression

BACKGROUND: Acute graft-versus-host disease (aGVHD) is a life-threatening complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Accumulating evidence suggests that imbalanced Treg/Th17 ratio accelerates the progression of aGVHD. The aryl hydrocarbon receptor (AhR) is a basi...

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Detalles Bibliográficos
Autores principales: Zeng, Cong, Cheng, Ting-ting, Ma, Xia, Liu, Yi, Hua, Juan, Chen, Xu, Wang, Shi-yu, Xu, Ya-jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440523/
https://www.ncbi.nlm.nih.gov/pubmed/36056390
http://dx.doi.org/10.1186/s13148-022-01330-7