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Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program

BACKGROUND: Epigenetic programming during development is essential for determining cell lineages, and alterations in this programming contribute to the initiation of embryonal tumour development. In neuroblastoma, neural crest progenitors block their course of natural differentiation into sympathoad...

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Detalles Bibliográficos
Autores principales: Jiménez, Carlos, Antonelli, Roberta, Nadal-Ribelles, Mariona, Devis-Jauregui, Laura, Latorre, Pablo, Solé, Carme, Masanas, Marc, Molero-Valenzuela, Adrià, Soriano, Aroa, Sánchez de Toledo, Josep, Llobet-Navas, David, Roma, Josep, Posas, Francesc, de Nadal, Eulàlia, Gallego, Soledad, Moreno, Lucas, Segura, Miguel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440539/
https://www.ncbi.nlm.nih.gov/pubmed/36057593
http://dx.doi.org/10.1186/s12943-022-01643-4