Induced hepatic stem cells maintain self-renewal through the high expression of Myc coregulated by TET1 and CTCF

BACKGROUND: Induced hepatic stem cells (iHepSCs) with the capacities of self-renewal and bidifferentiation into hepatocytes and cholangiocytes were generated from mouse embryonic fibroblasts (MEFs) by lineage reprogramming in our previous research. However, the mechanism of iHepSC self-renewal has n...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Yu, Xinlu, Ding, Sai, Liu, Yang, Zhang, Hongxia, Fu, Jingbo, Yu, Bing, Zhu, Haiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440563/
https://www.ncbi.nlm.nih.gov/pubmed/36056448
http://dx.doi.org/10.1186/s13578-022-00883-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440563/
https://www.ncbi.nlm.nih.gov/pubmed/36056448
http://dx.doi.org/10.1186/s13578-022-00883-7

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