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Induced hepatic stem cells maintain self-renewal through the high expression of Myc coregulated by TET1 and CTCF

BACKGROUND: Induced hepatic stem cells (iHepSCs) with the capacities of self-renewal and bidifferentiation into hepatocytes and cholangiocytes were generated from mouse embryonic fibroblasts (MEFs) by lineage reprogramming in our previous research. However, the mechanism of iHepSC self-renewal has n...

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Detalles Bibliográficos
Autores principales:	Wang, Chen, Yu, Xinlu, Ding, Sai, Liu, Yang, Zhang, Hongxia, Fu, Jingbo, Yu, Bing, Zhu, Haiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440563/ https://www.ncbi.nlm.nih.gov/pubmed/36056448 http://dx.doi.org/10.1186/s13578-022-00883-7

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