Deficiency of Jamc Leads to Congenital Nuclear Cataract and Activates the Unfolded Protein Response in Mouse Lenses

PURPOSE: The malfunction of junctional adhesion molecule C (JAM-C) has been reported to induce congenital cataract in humans and mice; however, specific characters and the mechanism of this cataract are still unclear. This study aimed to characterize abnormal lens development in Jamc knockout mice a...

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Detalles Bibliográficos
Autores principales: Li, Jiani, Tan, Xuhua, Sun, Qihang, Li, Xuri, Chen, Rongyuan, Luo, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Lens
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440611/
https://www.ncbi.nlm.nih.gov/pubmed/36048019
http://dx.doi.org/10.1167/iovs.63.10.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440611/
https://www.ncbi.nlm.nih.gov/pubmed/36048019
http://dx.doi.org/10.1167/iovs.63.10.1

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