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Gasdermin D Deficiency Does Not Protect Mice from High-Fat Diet-Induced Glucose Intolerance and Adipose Tissue Inflammation

The adipose tissue NLRP3 inflammasome has recently emerged as a contributor to obesity-related metabolic inflammation. Recent studies have demonstrated that the activation of the NLRP3 inflammasome cleaves gasdermin D (GSDMD) and induces pyroptosis, a proinflammatory programmed cell death. However,...

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Detalles Bibliográficos
Autores principales: Ma, Eun Bi, Javaid, Hafiz Muhammad Ahmad, Jung, Do-Hyeon, Park, Jong-Hwan, Huh, Joo Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440627/
https://www.ncbi.nlm.nih.gov/pubmed/36065376
http://dx.doi.org/10.1155/2022/7853482