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Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

In addition to investigating the virology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), discovering the host–virus dependencies are essential to identify and design effective antiviral therapy strategy. Here, we report that the SARS-CoV-2 entry receptor, ACE2, conjugates with smal...

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Detalles Bibliográficos
Autores principales: Jin, Shouheng, He, Xing, Ma, Ling, Zhuang, Zhen, Wang, Yiliang, Lin, Meng, Cai, Sihui, Wei, Lu, Wang, Zheyu, Zhao, Zhiyao, Wu, Yaoxing, Sun, Lin, Li, Chunwei, Xie, Weihong, Zhao, Yong, Songyang, Zhou, Peng, Ke, Zhao, Jincun, Cui, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440653/
https://www.ncbi.nlm.nih.gov/pubmed/36057605
http://dx.doi.org/10.1038/s41467-022-32957-y